The latest revolution in local control for bone tumors, both in people and dogs, is through minimally invasive ablative therapies. This is performed through a small incision, approximately 3–5mm in size, to allow a probe to enter the tumor and ablate the tumor from the inside. Commercially, there are three main temperature-based options: radiofrequency ablation, microwave ablation, and cryoablation. Heat ablation (RF and MWA) have garnered the most interest in veterinary medicine. Clinically, RFA and cementoplasty has now been performed in several dogs, which will be discussed. Additionally, a prospective clinical trial is underway for cryoablation and cementoplasty, of which preliminary data will be shared.